Sandra L Olmsted

CB 94

I’m part of the Organic Chemistry – Advanced Organic Chemistry team at Augsburg, teaching lectures and labs. In addition, I teach Principles of Medicinal Chemistry, my specialty area. In spring 2013 we launched a new course titled The Chemistry of Biological Systems, a true chemistry course, for chemistry majors, that examines chemical biology of both plant, animal, and prokaryotic life. This is all “where the fun is.” We have a fantastic group of students here and we love to bring them all to the highest level of achievement and understanding that they can attain. Inspiring them through coursework, research, and friendly conversation is our best contribution to the next generation of teachers, physicians, researchers, health professionals, and informed citizens.


  • B.A., Augsburg University (Major: Chemistry, ACS certified; Minor: Biology), 1969
  • M.S.,  University of Wisconsin, (Madison), Chemistry/Education (Curriculum and Instruction), 1973
  • Ph.D., University of Minnesota, Medicinal Chemistry, 1995

Research Interests

  • Building library of “scaffod molecules” for therapeutic and diagnostic nuclear medical applications
  • Green oxidation method development using catalytic aqueous copper sulfate
  • Dextran as drug delivery system to battle bacterial resistance

Recent Publications

  • Hanson, R.N.; Kirss, R.; McCaskill, E.; Hua, E.; Tongcharoensirikul, P.; Olmsted, S.L.; Labaree, D.; Hochberg, T.B., “Targeting the estrogen receptor with metal-carbonyl derivatives of estradiol”, Bioorganic & Medicinal Chemistry Letters, 22, (2012), 1670-1673.
  • Olmsted, S.; Hanson, R.N.; Tomgcharoensirikul, P.; McCaskill, E.; Gandiaga, K.; Labaree, D.; Hochberg, R.B., “Synthesis and evaluation of 17a-E-20-(heteroaryl) norpregn-1,3,5(10),20-tetraene-3,17b-diols[17a-(heteroaryl)vinyl estradiols] as ligands for the estrogen receptor a ligand binding domain (ERa-LBD)”; Bioorganic & Medicinal Chemistry Letters, 22, (2012), 977-979.
  • Pham, H.T.; Hanson, R.N.; Olmsted, S.L.; Kozhushnyan, A.; Visentin, A.; Weglinsky, P.J.; Massero, C.; Bailey, K., “Synthesis of 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)- Quinazoline”, Tetrahedron Letters 52 (2011) 1053–1056.